Nā huahana
Nā hōʻailona puʻuwai - Troponin I
ʻO Troponin kahi pūmua hoʻoponopono i nā ʻiʻo ʻiʻo i loko o nā ʻiʻo ʻiʻo, kahi e hoʻoponopono nui ai i ka hoʻoheheʻe ʻana ma waena o nā filament ʻiʻo mānoanoa a lahilahi i ka wā o ka hoʻopaʻa ʻana o ka myocardial.Ua haku ʻia ʻekolu mau ʻāpana: troponin T (TNT), troponin I (TNI) a me troponin C (TNC).Hoʻoponopono pū ʻia ka ʻōlelo o nā subtype ʻekolu i ka ʻiʻo iwi a me ka myocardium e nā ʻano genes like ʻole.ʻOi aku ka haʻahaʻa o ka ʻike o ka troponin cardiac i ka serum maʻamau ma mua o nā enzyme myocardial ʻē aʻe, akā kiʻekiʻe loa ka ʻike i ka cardiomyocytes.Ke paʻa ka membrane cell myocardial, ʻaʻole hiki i cTnI ke komo i ka membrane cell i loko o ke kahe koko.Ke loaʻa ka degeneration a me ka necrosis nā cell myocardial ma muli o ka ischemia a me ka hypoxia, hoʻokuʻu ʻia ka cTnI i loko o ke koko ma o nā membrane cell i poino.Hoʻomaka ka piʻi ʻana o ka cTnI i 3-4 mau hola ma hope o ka hiki ʻana o AMI, piʻi i nā hola 12-24, a hoʻomau no 5-10 mau lā.No laila, ua lilo ka hoʻoholo ʻana o ka cTnI i loko o ke koko i hōʻailona maikaʻi no ka nānā ʻana i ka pono o ka reperfusion a me ka reperfusion i nā maʻi AMI.ʻAʻole ʻo cTnI wale nō ka kikoʻī ikaika, akā he kiʻekiʻe kiʻekiʻe a me ka lōʻihi.No laila, hiki ke hoʻohana ʻia ka cTnI ma ke ʻano he hōʻailona koʻikoʻi e kōkua i ka ʻike ʻana i ka hōʻeha o ka myocardial, ʻoi aku ka nui o ka myocardial infarction.
Mea Nui
| Nā ʻāpana liʻiliʻi (M): | 0.13mg/ml ʻO nā microparticles i hui pū ʻia me ka anti troponin I ultra antibody |
| 1 (R1): | 0.1M Tris pale |
| Mea hoʻoponopono 2(R2): | 0.5μg/ml Alkaline phosphatase i kapa ʻia he antitroponin I ultra |
| Hoʻoponopono hoʻomaʻemaʻe: | 0.05% surfactant, 0.9% Sodium chloride pale |
| Pāpala: | AMPPD i ka AMP buffer |
| Calibrator （ke koho）： | Troponin I ultra antigen |
| Mea hoʻomalu （ koho）： | Troponin I ultra antigen |
Nānā:
1. ʻAʻole hiki ke hoʻololi ʻia nā ʻāpana ma waena o nā pūʻulu o nā ʻāpana reagent;
2.E nānā i ka lepili o ka'ōmole calibrator no ka hoʻonuiʻana i ka calibrator;
3. Eʻike i ka lepili'ōmole hoʻomalu no ka laulā o nā mana.
Waihona a me ka pono
1.Storage: 2 ℃ ~ 8 ℃, pale pono i ka lā.
2.Validity: pono nā huahana i wehe ʻole ʻia no nā mahina 12 ma lalo o nā kūlana i kuhikuhi ʻia.
3.Calibrators a me nā mana ma hope o ka hoʻoheheʻe ʻana hiki ke mālama ʻia no 14 mau lā ma 2 ℃ ~ 8 ℃ pōʻeleʻele.
Mea hana pili
Pūnaehana CLIA Automated o Illumaxbio (lumiflx16、lumiflx16s、lumilite8、 lumilite8s).
